Here's the initial route for the info that I plugged in. Three rest stops at the ~2-hour marks. Can easily be tweaked for lots of stuff. It also has the ability to plan for gassing up based on tank size and MPG.
Time Mile Instruction For Toward
Summary: 549.3 miles (8 hours, 40 minutes)
8:00 AM 0.0 Depart Wyndham-Northwest Chicago [400 Park Blvd, Itasca IL 60143, United States, Tel: +1 (630) 773-4000] on Local road(s) (South) 120 yds
8:00 AM 0.1 Turn RIGHT (West) onto CR-26 [Thorndale Ave] 0.1 mi Elgin-O'Hare Expressway
8:00 AM 0.2 Take Ramp (RIGHT) onto I-290 10.6 mi I-290 / Chicago
8:12 AM 10.8 At exit 15A, turn RIGHT onto Ramp 0.4 mi I-294 / Indiana
8:12 AM 11.2 *Toll road* Merge onto I-294 [Tri-State Tollway] 26.1 mi
8:39 AM 37.3 Take Ramp (RIGHT) onto I-80 3.5 mi I-80 / I-57 S / Iowa
8:43 AM 40.8 At exit 151A, take Ramp (LEFT) onto I-57 92.6 mi I-57 / Memphis
Resurfacing between Ashkum and Gilman (SB) (July 12, 2010 - November 30, 2010)
10:02 AM 133.4 Rest break (15 mins)
10:17 AM 133.4 Stay on I-57 (South-West) 143.6 mi
Construction between Mattoon and Arcola (SB) (January 18, 2010 - November 19, 2010)
12:18 PM 276.9 Rest break (15 mins)
12:33 PM 276.9 At exit 109, stay on I-57 (South) 131.5 mi
12:37 PM 281.6 Refuel before here (last refuel was 281.6 miles ago)
Construction between West City and West Frankfort (SB) (September 30, 2010 - February 28, 2011)
2:05 PM 386.4 Entering Missouri
2:24 PM 408.5 At exit 1A, take Ramp (RIGHT) onto I-55 14.2 mi I-55 / Memphis
2:36 PM 422.7 Rest break (15 mins)
2:51 PM 422.7 At exit 52, stay on I-55 (South) 118.0 mi
3:35 PM 475.1 Entering Arkansas
4:31 PM 540.7 Merge onto I-40 [I-55] 7.5 mi
4:37 PM 547.7 Entering Tennessee
4:38 PM 548.2 At exit 1, turn RIGHT onto Ramp 0.2 mi Riverside Dr / Front St
4:38 PM 548.5 Keep RIGHT to stay on Ramp 0.3 mi Riverside Dr / Front St
4:38 PM 548.8 Keep STRAIGHT onto Arkansas-Riverside Dr [N Riverside Dr] 0.3 mi
4:39 PM 549.0 Turn LEFT (East) onto Monroe Ave 0.3 mi
4:40 PM 549.3 Arrive 211 Monroe Ave, Memphis, TN 38103
SUMMARY
Driving distance: 549.3 miles
Trip duration: 8 hours, 40 minutes
Driving time: 7 hours, 55 minutes
Cost: $97.38
Time Mile Instruction For Toward
Summary: 549.3 miles (8 hours, 40 minutes)
8:00 AM 0.0 Depart Wyndham-Northwest Chicago [400 Park Blvd, Itasca IL 60143, United States, Tel: +1 (630) 773-4000] on Local road(s) (South) 120 yds
8:00 AM 0.1 Turn RIGHT (West) onto CR-26 [Thorndale Ave] 0.1 mi Elgin-O'Hare Expressway
8:00 AM 0.2 Take Ramp (RIGHT) onto I-290 10.6 mi I-290 / Chicago
8:12 AM 10.8 At exit 15A, turn RIGHT onto Ramp 0.4 mi I-294 / Indiana
8:12 AM 11.2 *Toll road* Merge onto I-294 [Tri-State Tollway] 26.1 mi
8:39 AM 37.3 Take Ramp (RIGHT) onto I-80 3.5 mi I-80 / I-57 S / Iowa
8:43 AM 40.8 At exit 151A, take Ramp (LEFT) onto I-57 92.6 mi I-57 / Memphis
Resurfacing between Ashkum and Gilman (SB) (July 12, 2010 - November 30, 2010)
10:02 AM 133.4 Rest break (15 mins)
10:17 AM 133.4 Stay on I-57 (South-West) 143.6 mi
Construction between Mattoon and Arcola (SB) (January 18, 2010 - November 19, 2010)
12:18 PM 276.9 Rest break (15 mins)
12:33 PM 276.9 At exit 109, stay on I-57 (South) 131.5 mi
12:37 PM 281.6 Refuel before here (last refuel was 281.6 miles ago)
Construction between West City and West Frankfort (SB) (September 30, 2010 - February 28, 2011)
2:05 PM 386.4 Entering Missouri
2:24 PM 408.5 At exit 1A, take Ramp (RIGHT) onto I-55 14.2 mi I-55 / Memphis
2:36 PM 422.7 Rest break (15 mins)
2:51 PM 422.7 At exit 52, stay on I-55 (South) 118.0 mi
3:35 PM 475.1 Entering Arkansas
4:31 PM 540.7 Merge onto I-40 [I-55] 7.5 mi
4:37 PM 547.7 Entering Tennessee
4:38 PM 548.2 At exit 1, turn RIGHT onto Ramp 0.2 mi Riverside Dr / Front St
4:38 PM 548.5 Keep RIGHT to stay on Ramp 0.3 mi Riverside Dr / Front St
4:38 PM 548.8 Keep STRAIGHT onto Arkansas-Riverside Dr [N Riverside Dr] 0.3 mi
4:39 PM 549.0 Turn LEFT (East) onto Monroe Ave 0.3 mi
4:40 PM 549.3 Arrive 211 Monroe Ave, Memphis, TN 38103
SUMMARY
Driving distance: 549.3 miles
Trip duration: 8 hours, 40 minutes
Driving time: 7 hours, 55 minutes
Cost: $97.38
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